PROF. DATO' Dr. RIDZWAN

Member of the International Network for Holothurian (sea cucumber) Conservation and Sustainable Management.

Recognised by the Malaysia Book of Records Millennium being the first to rear sea cucumber (Stichopus horrens) in cages.

Nominee for UNESCO Kalinga Prized for the Popularization of Sciences 2009 to represent
Malaysia.

Besides being the author of several books on gamat (sea cucumbers) including Timun Laut - Warisan Malaysia (2010) & international journals contribution , parts of his work were also documented in VCDs by the Department of Museums and Antiquities Malaysia (Penyelidikan Gamat di Sabah) and Filem Negara Malaysia.

He was Bestowed in 2007 by His Royal Highness the Sultan of Kelantan State, "Darjah Kebesaran Paduka Mahkota Kelantan Yang Amat Mulia Peringkat Ketiga, PMK".

Later, in 2014 he was again bestowed 'Ahli Yang Kedua (Dato' Paduka) Jiwa Mahkota Kelantan Yang AmatMulia, D.J.M.K'.

ANALGESIC EFFECT

Ridzwan,B.H., Leong, T.C. & Idid, S.Z (2003):Coelomic fluid of S.horrens has antinociceptive effect in mice as evaluated using abdomen constriction test on pain induced mice with acetic acid[Source:Pakistan J. Biological Sci. 6 (24)].

Zarina, M.Z. (1999):Stichopus. mempunyai kesan analgestik dalam ujian kuis ekor pada mencit. (Source: Timun Laut Warisan Malaysia, 2010)

STEM CELL

Siti Nurnasihah et al. (2014): Stichopus horrens is suggested as a promising role in promoting stem cell proliferation. (Source: Health and Life Sciences Postgraduate Conferences. 10-11 June, Kelantan, Malaysia)

ANTICANCER ACTIVITY

Osama et al. (2011):Stichopus horrens has high antioxidant activity and has some inhibitory effect on growth of three cancer cells (cervical, breast and lungs). (Source: IRIIE, IIUM Gombak)

DIABETES MELLITUS

Shila Arwina, R. (2000): Coelomic fluid and extract of Stichopus horrens reduced blood glucose level in diabetic induced rats (Source: Timun Laut Warisan Malaysia, 2010)

LIVER DAMAGE

Idid, S.Z., Azidah, A.A. & Ridzwan, B.H. (2003): kerosakan hati tikus aruhan alkohol........setelah dirawat dengan bendalir selom S. horrens, kadar metabolisme katekolamin dalam tunjang otak menurun kepada 7 kali ganda normal iaitu 30% kemajuan. (Source: Int. Conf. Advancement Sci. Tech. iCAST 2003, IIUM, KL)

ASTHMA

Ridzwan et al. (1990): crude extract S. horrens had anti-anaphylaxis effects on anaphylaxic induced guinea-pigs either with histamine or albumin(Source: Simp. Bio. Gunaan Malaysia I. Universiti Pertanian Malaysia, Serdang).

HEART

Tan, W.T., Yew, S.F. & Ridzwan, B.H. (2005):Bendalir Stichopus sp. mengurangkan kadar denyutan jantung terpisah tikus, kontraktiliti..vasodilatasi saluran koronari...[Source:Pakistan J. Biological Sci. 8(1)].

Suhadah, A. (2003):The vasorelaxation of coelomic fluid Stichopus horrens involved calcium channel(Source: Timun Laut Warisan Malaysia, 2010)

Yew et al.(2003 ): Coelomic fluid has relaxation effects on the isolated aortic rings of rats.... this relaxation does not involve nitrous oxide (NO). (Source: Int. Conf. Advancement Sci. Tech. iCAST 2003, IIUM, KL).

BLOOD PRESSURE

Mohd Noor, B.I. ,Wan Norizan, B. &Ridzwan, B.H. (2001):Crude extract Stichopus horrens and commercial gamat water were able to reduce blood pressure on rats induced hypertension using fructose. [(Source:Asia Pacific J. Pharmacology 15(Suppl I)].

ANTIMICROBIAL ACTIVITY

Zainal Abidin et al. (2000): Water extract from Stichopus horrens showed inhibitory effects towards Norcadia sp. (Source: Pasca Simp. Sains Kesihatan Kebangsaan ke-3, FSKB, UKM)

ANTIOXIDANT AND ANTIPROLIFERATIVES

Osama et al. (2010): Stichopus horrenshas antioxidant and antiproliferatives. (Source: 3rd Int. Conf. Young Chem. Universiti Sains Malaysia. 23rd - 25th June 2010. Nat-011)

WOUND HEALING

Ping L.S., Mohd Noor, B.I. & Ridzwan B.H. (2000):Pemerhatian dermatologi menggunakan imbasan mikroskop elektron (SEM ) menunjukkan penyembuhan luka dengan ekstrak Stichopus horrens menghasilkan permukaan kerotin yang licin serta halus berbanding dengan kawalan dan rawatan dengan probidon iodin. (Source: 9th Sci. Conf. Electron Microscopic Soc. 12-14th Nov. 2000. Kota Bharu, Kelantan).

Ridzwanet et al.(2014): Stichopus horrens contains arachidonic acid (AA), eicosapentanoic acid (EPA) and docosahexanoic acid (DHA). (Source: Int. J. Biosci. Biochem. Bioinform. 4(3). 2014)

PLEURISIES (LUNGS)

Jamiah et al. (2001):Ekstrak ethanol Stichopus horrens. berupaya mengurangkan kecederaan plural, penurunan aktiviti adenosine deaminase, aras serotonin dan bilangan leukosit berbang dengan tikus pleurisies kawalan..(Source: Asia Pacific J. Pharmacol. IS(1) : S33)

GASTRIC ULCER

Nihayah et al. (2000) and Yanti et al. (2000):Extract Stichopus horrens enhance mucous production and heal gastric ulcer induced by acetic acid and reserpine, respectively. (Source: Pasca Simp. Sains Kesihatan Kebangsaan ke-3,29-30 April, FSKB, UKM)

ARTHRITIS

Ridzwan et al. (2001):Mendapati bendalir selom Stichopus horrens mengandungi agen anti arthritis di mana berlaku pengurangan darjah fleksi lutut pada tikus belanda diaruh arthritis dengan antigen. (Source:The Sci. Conf. 2001 Yemeni Sci. Res. Foundation, 11-13th Oct., Sana's Yemen)